The sterilising-grade filters Sartopore from Sartorius Stedim Biotech are pleated using the TwinPleat process. The surface of the polyethersulfone filter membrane has been modified using a hydrophilic and highly thermostable polymer. This surface modification gives the membrane good wetting properties and minimises its protein binding. Fewer than five liters of WFI are needed to wet a 10″ Sartopore Platinum cartridge fast and reliably for subsequent integrity testing that provides dependably accurate results.
The membrane’s minimised protein binding considerably increases product yield, thus augmenting the efficiency of manufacturing processes. Sartopore Platinum filter cartridges
can be dry-steam sterilised in the forward or the reverse direction, without altering the properties of their membrane. The filters can be used in the entire pH range from 1 to 14 and thus for nearly any filtration application in biopharmaceutical manufacturing.
cpp-net.com/0312410
Share:
