The Niro Two-Fluid Nozzle (NTF) is a spray-drying nozzle that produces fine particles, with a narrow size distribution, and high capacity production using limited amounts of atomizing gas. The NTF has been developed specifically to produce pharmaceutical powders for inhalation. The NTF operates with both feed liquid and propellant gas to produce a mean particle size of less than 10 µm and a span of less than 2. Liquid feed rates range from 30 to 80 l/h and droplet formation can be varied by adjusting the gas-to-feed ratio. The NTF can also handle feeds with high solids content and is designed to be easy to clean and for use under GMP conditions.
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